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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 81035 | COLEC12 | collectin subfamily member 12 | |
| 81890 | QTRT1 | queuine tRNA-ribosyltransferase catalytic subunit 1 | |
| 116255 | MOGAT1 | monoacylglycerol O-acyltransferase 1 | |
| 120227 | CYP2R1 | cytochrome P450 family 2 subfamily R member 1 | |
| 151056 | PLB1 | phospholipase B1 | |
| 160364 | CLEC12A | C-type lectin domain family 12 member A | |
| 253782 | CERS6 | ceramide synthase 6 | |
| 285362 | SUMF1 | sulfatase modifying factor 1 | |
| 285704 | RGMB | repulsive guidance molecule BMP co-receptor b | |
| 100507436 | MICA | MHC class I polypeptide-related sequence A |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 16002 | Igf2 | insulin-like growth factor 2 | |
| 21898 | Tlr4 | toll-like receptor 4 | |
| 21926 | Tnf | tumor necrosis factor | |
| 56336 | B4galt5 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 | |
| 56386 | B4galt6 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 | |
| 100198 | H6pd | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 43222 | Tl | Toll | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q15392 | Delta(24)-sterol reductase | |
| Q16678 | Cytochrome P450 1B1 | |
| Q29983 | MHC class I polypeptide-related sequence A | |
| Q2KHT3 | Protein CLEC16A | |
| Q5KU26 | Collectin-12 | |
| Q5QGZ9 | C-type lectin domain family 12 member A | |
| Q6NW40 | Repulsive guidance molecule B | |
| Q6P1J6 | Phospholipase B1, membrane-associated | |
| Q6ZMG9 | Ceramide synthase 6 | |
| Q8N6G5 | Chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
