glioblastoma

Summary
Synonym
  • GBM
  • adult glioblastoma multiforme
  • glioblastoma multiforme
  • grade IV adult Astrocytic tumor
  • primary glioblastoma multiforme
  • spongioblastoma multiforme
Definition
A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Super Class
malignant astrocytoma
External Links
Disease Ontology
DOID:3068
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 131 - 140 of 262 in total
Gene ID Gene Symbol Description Source
5289 PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
5305 PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
5310 PKD1 polycystin 1, transient receptor potential channel interacting
5311 PKD2 polycystin 2, transient receptor potential cation channel
5315 PKM pyruvate kinase M1/2
5321 PLA2G4A phospholipase A2 group IVA
Displaying all 5 entries
Gene ID Gene Symbol Description Source
12654 Chi3l1 chitinase 3 like 1
15926 Idh1 isocitrate dehydrogenase 1 (NADP+), soluble
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
18654 Pgf placental growth factor
22059 Trp53 transformation related protein 53
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24842 Tp53 tumor protein p53
85496 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
89824 Chi3l1 chitinase 3 like 1
94203 Pgf placental growth factor
Displaying all 6 entries
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
Displaying 1 entry
Gene ID Gene Symbol Description Source
180628 cht-1 putative endochitinase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024