bone osteosarcoma

Summary
Synonym
  • Osteosarcoma of bone
  • primary Osteosarcoma of bone
Definition
An osteosarcoma that is an usually aggressive malignant bone-forming mesenchymal neoplasm arising from the bone. It may arise de novo or from a pre-existing lesion of the bone. Pain and a palpable mass are the most frequent clinical sign and symptom. It may spread to other anatomic sites, particularly the lungs.
Super Class
osteosarcoma
External Links
Disease Ontology
DOID:3376
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 150 in total
Gene ID Gene Symbol Description Source
47 ACLY ATP citrate lyase
98 ACYP2 acylphosphatase 2
142 PARP1 poly(ADP-ribose) polymerase 1
219 ALDH1B1 aldehyde dehydrogenase 1 family member B1
226 ALDOA aldolase, fructose-bisphosphate A
240 ALOX5 arachidonate 5-lipoxygenase
248 ALPI alkaline phosphatase, intestinal
249 ALPL alkaline phosphatase, biomineralization associated
250 ALPP alkaline phosphatase, placental
308 ANXA5 annexin A5

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024