human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 31 - 40 of 56 in total
Gene ID Gene Symbol Description Source
4988 OPRM1 opioid receptor mu 1
5133 PDCD1 programmed cell death 1
5243 ABCB1 ATP binding cassette subfamily B member 1
5265 SERPINA1 serpin family A member 1
5320 PLA2G2A phospholipase A2 group IIA
5329 PLAUR plasminogen activator, urokinase receptor
5478 PPIA peptidylprolyl isomerase A
5551 PRF1 perforin 1
5743 PTGS2 prostaglandin-endoperoxide synthase 2
6059 ABCE1 ATP binding cassette subfamily E member 1
Displaying entries 41 - 50 of 62 in total
Gene ID Gene Symbol Description Source
20704 Serpina1e serine (or cysteine) peptidase inhibitor, clade A, member 1E
21926 Tnf tumor necrosis factor
21939 Cd40 CD40 antigen
21947 Cd40lg CD40 ligand
24015 Abce1 ATP-binding cassette, sub-family E member 1
58217 Trem1 triggering receptor expressed on myeloid cells 1
60504 Il21r interleukin 21 receptor
60505 Il21 interleukin 21
60533 Cd274 CD274 antigen
69165 Cd209b CD209b antigen
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
246097 Fas Fas cell surface death receptor
304966 Fcgr3a Fc gamma receptor 3A
353253 Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
365769 Il21 interleukin 21
100360977 Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D
Displaying all 4 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
36016 Sting sting
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 4 entries
Gene ID Gene Symbol Description Source
173794 vab-1 Ephrin receptor 1
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
188252 lev-9 Protein lev-9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851665 RLI1 Fe-S cluster-binding ribosome biosynthesis protein
853671 STE6 ATP-binding cassette a-factor transporter STE6

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Last updated: December 9, 2024