acquired immunodeficiency syndrome

Summary
Synonym
  • AIDS
  • acquired Immune deficiency
Definition
A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS.
Super Class
human immunodeficiency virus infectious disease
Disease Ontology
DOID:635
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
684 BST2 bone marrow stromal cell antigen 2
920 CD4 CD4 molecule
925 CD8A CD8 subunit alpha
968 CD68 CD68 molecule
3105 HLA-A major histocompatibility complex, class I, A
3481 IGF2 insulin like growth factor 2
3802 KIR2DL1 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
3813 KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
5243 ABCB1 ATP binding cassette subfamily B member 1
7124 TNF tumor necrosis factor
Displaying entries 1 - 10 of 24 in total
Gene ID Gene Symbol Description Source
12504 Cd4 CD4 antigen
12514 Cd68 CD68 antigen
12525 Cd8a CD8 subunit alpha
14964 H2-D1 histocompatibility 2, D region locus 1
14972 H2-K1 histocompatibility 2, K1, K region
15006 H2-Q1 histocompatibility 2, Q region locus 1
15007 H2-Q10 histocompatibility 2, Q region locus 10
15013 H2-Q2 histocompatibility 2, Q region locus 2
15015 H2-Q4 histocompatibility 2, Q region locus 4
15018 H2-Q7 histocompatibility 2, Q region locus 7
Displaying all 9 entries
Gene ID Gene Symbol Description Source
24483 Igf2 insulin-like growth factor 2
24835 Tnf tumor necrosis factor
24930 Cd8a CD8 subunit alpha
24932 Cd4 Cd4 molecule
25625 Tnfrsf1a TNF receptor superfamily member 1A
117547 Ncr1 natural cytotoxicity triggering receptor 1
156767 Tnfrsf1b TNF receptor superfamily member 1B
353253 Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
378947 Bst2 bone marrow stromal cell antigen 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 2 entries
Gene ID Gene Symbol Description Source
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6

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Last updated: December 9, 2024