appendicitis

Summary
Synonym
  • acute appendicitis
  • acute appendicitis with generalized peritonitis
  • acute appendicitis with peritoneal abscess
Definition
An appendix disease that involves inflammation and infection of the appendix caused by the blockage of the lumen with a small, hard piece of stool, a foreign body or worms. Mucus backs up in the appendiceal lumen, causing bacteria that live inside the appendix to multiply. The infection has_symptom pain, in the upper abdomen initially and later in the lower abdomen, has_symptom nausea, has_symptom vomiting and has_symptom fever.
Super Class
appendix disease
Disease Ontology
DOID:8337
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying 1 entry
Gene ID Gene Symbol Description Source
2147 F2 coagulation factor II, thrombin
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
P00734 Prothrombin

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025