amyloidosis

Summary
Synonym
  • amyloid disease
Definition
A disease of metabolsism that is characterized by extracellular tissue deposition of mis-folded amyloid fibrils built up by twisted protofilaments, deposited in the spaces between the cells of vital organs, causing disruption of organ tissue structure and function. These deposits may result in a wide range of clinical manifestations depending upon their type, location, and the amount of deposition.
Super Class
disease of metabolism
Disease Ontology
DOID:9120
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 9 entries
Gene ID Gene Symbol Description Source
325 APCS amyloid P component, serum
1435 CSF1 colony stimulating factor 1
2805 GOT1 glutamic-oxaloacetic transaminase 1
5054 SERPINE1 serpin family E member 1
7124 TNF tumor necrosis factor
7132 TNFRSF1A TNF receptor superfamily member 1A
7276 TTR transthyretin
9370 ADIPOQ adiponectin, C1Q and collagen domain containing
54210 TREM1 triggering receptor expressed on myeloid cells 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
12977 Csf1 colony stimulating factor 1 (macrophage)
14718 Got1 glutamic-oxaloacetic transaminase 1, soluble
20219 Apcs amyloid P component, serum
21926 Tnf tumor necrosis factor
21937 Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a
22139 Ttr transthyretin
58217 Trem1 triggering receptor expressed on myeloid cells 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source
24401 Got1 glutamic-oxaloacetic transaminase 1
24617 Serpine1 serpin family E member 1
24835 Tnf tumor necrosis factor
24856 Ttr transthyretin
25625 Tnfrsf1a TNF receptor superfamily member 1A
29339 Apcs amyloid P component, serum
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
397787 ttr.L transthyretin L homeolog Xenopus laevis (African clawed frog)
Displaying 1 entry
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein

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Last updated: December 9, 2024