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Guidelines
MIRAGE
tumor necrosis factor
Summary
- Gene Symbol
-
- TNF
- Organism
- Oryctolagus cuniculus (rabbit)
Annotation
- Keyword
-
- Cell membrane
- Cytokine
- Disulfide bond
- Myristate
- Phosphoprotein
- Reference proteome
- Secreted
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A5S8H7U2 |
|
| A0A0U5CJJ9 |
|
| P04924 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| microglial cell activation |
|
|
| negative regulation of endothelial cell proliferation |
|
|
| macrophage activation involved in immune response |
|
|
| chronic inflammatory response to antigenic stimulus |
|
GO Hierarchy
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- regulation of membrane lipid metabolic process
- regulation of reactive oxygen species metabolic process
- positive regulation of synaptic transmission
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of synaptic transmission
- positive regulation of synaptic transmission
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of hair follicle development
- positive regulation of synaptic transmission
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- regulation of membrane lipid metabolic process
- regulation of reactive oxygen species metabolic process
- positive regulation of synaptic transmission
- positive regulation of nitric oxide biosynthetic process
- positive regulation of vitamin D biosynthetic process
- positive regulation of hair follicle development
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of protein metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of amide metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of protein metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of protein metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of nitrogen compound metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of signal transduction [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of protein localization [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
positive regulation of signal transduction [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of anatomical structure morphogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of DNA-templated transcription [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation [inference]
positive regulation of cell communication [inference]
positive regulation of signal transduction [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression [inference]
positive regulation of cytokine production [inference]
positive regulation of protein localization [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
negative regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| phagocytic cup |
|
|
| extracellular space | ||
| external side of plasma membrane |
|
|
| cell surface | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transcription cis-regulatory region binding |
|
|
| protease binding |
|
|
| cytokine activity | ||
| tumor necrosis factor receptor binding | ||
| death receptor agonist activity |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- tumor necrosis factor
- Functional Category
-
- L: Replication, recombination and repair
- O: Posttranslational modification, protein turnover, chaperones
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7124 | HUMAN83918 | ||
| 21926 | MOUSE20698 | ||
| 24835 | RATNO21568 | ||
| 397086 | PIGXX31150 | ||
| 403922 | CANLF02543 | ||
| 443540 | SHEEP10443 | ||
| 494186 | PANTR37685 | ||
| 715467 | MACMU33860 | ||
| 100023069 | MONDO10816 | ||
| 100033834 | HORSE19385 |
