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selectin E

Summary

Gene Symbol

SELE

Organism

Oryctolagus cuniculus (rabbit)

External Links

NCBI Gene: 100009151
KEGG Gene ID: ocu:100009151
PubChem: 100009151

Annotation

Keyword

Calcium
Cell adhesion
Cell membrane
Disulfide bond
EGF-like domain
Glycoprotein
Lectin
Metal-binding
Reference proteome
Repeat
Signal
Sushi
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P27113	CD62 antigen-like family member E Endothelial leukocyte adhesion molecule 1 Leukocyte-endothelial cell adhesion molecule 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
leukocyte tethering or rolling	IEA	30032202
response to cytokine	IEA	30032202
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IEA	30032202
positive regulation of leukocyte tethering or rolling
cell adhesion

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

Displaying **all 4** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA	30032202
membrane	IEA	22301074
plasma membrane
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
metal ion binding
sialic acid binding	IEA	30032202
carbohydrate binding
oligosaccharide binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding

oligosaccharide binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

sialic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

sialic acid binding

cation binding [inference]

metal ion binding

carbohydrate derivative binding [inference]

sialic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sushi domain-containing protein

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

KEGG BRITE Database

Orthology

K06494

Name

selectin, endothelial cell

References

1689848

Ortholog

Displaying entries **81 - 85** of 85 in total

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Species	Gene ID	OrthoDB
Phodopus roborovskii	127223269	109678_0:001f86
Apodemus sylvaticus	127697490	10129_0:0039d8
Ochotona princeps	131478186	9978_0:000871
Ochotona princeps	131478190	9978_0:000812
Peromyscus eremicus	131925733	42410_0:003f5f

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements