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galectin 3

Summary

Gene Symbol

LGALS3

Organism

Oryctolagus cuniculus (rabbit)

External Links

NCBI Gene: 100009187
KEGG Gene ID: ocu:100009187
PubChem: 100009187

Annotation

Keyword

Acetylation
Cytoplasm
Differentiation
Disulfide bond
IgE-binding protein
Innate immunity
Lectin
Nucleus
Phosphoprotein
Reference proteome
Repeat
Secreted
Spliceosome

Proteins

Displaying 1 entry
UniProt	Protein Name
P47845	35 kDa lectin Carbohydrate-binding protein 35 Galactose-specific lectin 3 IgE-binding protein Laminin-binding protein Lectin L-29 Mac-2 antigen

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
macrophage chemotaxis	IEA	30032202
positive chemotaxis	IEA	30032202
monocyte chemotaxis	IEA	30032202
eosinophil chemotaxis	IEA	30032202
positive regulation of calcium ion import	IEA	30032202

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil migration [inference]

eosinophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

macrophage migration [inference]

macrophage chemotaxis

cellular process [inference]

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

mononuclear cell migration [inference]

monocyte chemotaxis

myeloid leukocyte migration [inference]

monocyte chemotaxis

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil migration [inference]

eosinophil chemotaxis

neutrophil migration [inference]

neutrophil chemotaxis

macrophage migration [inference]

macrophage chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

locomotion [inference]

taxis [inference]

chemotaxis [inference]

positive chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

regulation of calcium ion import [inference]

positive regulation of calcium ion import

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion import

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of apoptotic signaling pathway [inference]

negative regulation of extrinsic apoptotic signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
collagen-containing extracellular matrix	IEA	30032202
extracellular space	IEA	30032202
immunological synapse	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
laminin binding	IEA	30032202
carbohydrate binding	IEA	22301074
IgE binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

laminin binding

carbohydrate binding

protein-containing complex binding [inference]

immunoglobulin binding [inference]

IgE binding

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K06831

Name

galectin-3

References

2261464

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Orthologous MAtrix
Callorhinchus milii	103178496	CALMI15502
Crocodylus porosus	109320660	CROPO08627
Pseudonaja textilis	113435112	PSETE05864
Ornithorhynchus anatinus	100082735	ORNAN06125
Sarcophilus harrisii	100929541	SARHA15349
Callithrix jacchus	100404077	CALJA02607
Cercocebus atys	105586649	CERAT19623
Macaca fascicularis	102145569	MACFA39270
Macaca mulatta	697290	MACMU39910
Macaca nemestrina	105481782	MACNE22728