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alcohol dehydrogenase 5 (class III), chi polypeptide

Summary

Gene Symbol

ADH5

Organism

Oryctolagus cuniculus (rabbit)

External Links

NCBI Gene: 100009307
KEGG Gene ID: ocu:100009307
PubChem: 100009307

Annotation

Keyword

Acetylation
Cytoplasm
Lipid metabolism
Metal-binding
NAD
Oxidoreductase
Phosphoprotein
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
O19053	Alcohol dehydrogenase 5 Alcohol dehydrogenase class-III Glutathione-dependent formaldehyde dehydrogenase S-(hydroxymethyl)glutathione dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
formaldehyde catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

small molecule catabolic process [inference]

formaldehyde catabolic process

organic substance catabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

formaldehyde metabolic process [inference]

formaldehyde catabolic process

cellular catabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

small molecule metabolic process [inference]

small molecule catabolic process [inference]

formaldehyde catabolic process

formaldehyde metabolic process [inference]

formaldehyde catabolic process

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

formaldehyde metabolic process [inference]

formaldehyde catabolic process

organic substance catabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

formaldehyde metabolic process [inference]

formaldehyde catabolic process

cellular catabolic process [inference]

aldehyde catabolic process [inference]

formaldehyde catabolic process

cellular detoxification [inference]

cellular detoxification of aldehyde [inference]

formaldehyde catabolic process

detoxification [inference]

cellular detoxification [inference]

cellular detoxification of aldehyde [inference]

formaldehyde catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
zinc ion binding	IEA	22301074 30032202
alcohol dehydrogenase activity, zinc-dependent	IEA	30032202
S-(hydroxymethyl)glutathione dehydrogenase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity [inference]

alcohol dehydrogenase activity, zinc-dependent

S-(hydroxymethyl)glutathione dehydrogenase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00121

Name

S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]

References

Rhea

RHEA:19981

NADP⁺ + S-(hydroxymethyl)glutathione

H⁺ + S-formylglutathione + NADPH

Enzyme

1.1.1.284

PMID

RHEA:19985

NAD⁺ + S-(hydroxymethyl)glutathione

H⁺ + S-formylglutathione + NADH

Enzyme

1.1.1.284

PMID

RHEA:10736

a primary alcohol + NAD⁺

H⁺ + an aldehyde + NADH

Enzyme

PMID

RHEA:10740

a secondary alcohol + NAD⁺

H⁺ + a ketone + NADH

Enzyme

1.1.1.1

PMID

RHEA:25290

ethanol + NAD⁺

acetaldehyde + H⁺ + NADH

Enzyme

1.1.1.1

PMID

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Orthologous MAtrix
Ciona intestinalis	445671	CIOIN05226
Callorhinchus milii	103188743	CALMI39805
Callorhinchus milii	121851506	CALMI39805
Latimeria chalumnae	102353852	LATCH02984
Danio rerio	116517	DANRE06735
Astyanax mexicanus	103043395	ASTMX03771
Ictalurus punctatus	108269088	ICTPU34772
Electrophorus electricus	113568459	ELEEL49936
Salmo salar	106611602	SALSA145297
Salmo trutta	115170864	SALTR45457

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements