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Guidelines

MIRAGE

phospholipase B1

Summary

Gene Symbol

PLB1

Organism

Oryctolagus cuniculus (rabbit)

External Links

NCBI Gene: 100009309
KEGG Gene ID: ocu:100009309
PubChem: 100009309

Annotation

Keyword

Cell membrane
Glycoprotein
Hydrolase
Phospholipid metabolism
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q05017	Lysophospholipase Phospholipase A2 Phospholipase AdRab-B Phospholipase B/lipase Triacylglycerol lipase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phospholipid metabolic process	IEA	30032202
phosphatidylcholine catabolic process
diacylglycerol catabolic process
monoacylglycerol catabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organonitrogen compound catabolic process [inference]

phosphatidylcholine catabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

monoacylglycerol metabolic process [inference]

monoacylglycerol catabolic process

acylglycerol catabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylcholine catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
apical plasma membrane
brush border membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
lysophospholipase activity	IEA	30032202
phospholipase A2 activity	IEA	30032202
triglyceride lipase activity
phospholipase A1 activity
acylglycerol lipase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

lysophospholipase activity

phospholipase A2 activity

calcium-independent phospholipase A2 activity

phospholipase A1 activity

carboxylic ester hydrolase activity [inference]

lysophospholipase activity

phospholipase A2 activity

calcium-independent phospholipase A2 activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phospholipase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
hydrolase activity, acting on ester bonds
phospholipase activity
phospholipid metabolic process
retinyl-palmitate esterase activity

Displaying **all 4** entries
InterPro
GDSL lipase/esterase
Phospholipase B1, membrane-associated
Phospholipase B
SGNH hydrolase superfamily

KEGG BRITE Database

Orthology

K14621

Name

phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]

References

Rhea

H₂O + a 1,2-diacyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + a 1-acyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

H₂O + a triacylglycerol

H⁺ + a diacylglycerol + a fatty acid

Enzyme

PMID

H₂O + a 1-acyl-sn-glycero-3-phosphocholine

H⁺ + sn-glycerol 3-phosphocholine + a fatty acid

Enzyme

3.1.1.5

PMID

H₂O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + 1-O-alkyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

9442064

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025