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matrix metallopeptidase 13

Summary

Gene Symbol

MMP13

Organism

Equus caballus (horse)

External Links

NCBI Gene: 100009711
PubChem: 100009711

Annotation

Keyword

Calcium
Collagen degradation
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Phosphoprotein
Reference proteome
Repeat
Signal
Zinc
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
O18927	Matrix metalloproteinase-13

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteolysis	IEA	22301074
extracellular matrix disassembly
extracellular matrix organization	IEA	30032202
collagen catabolic process	IEA	30032202
bone morphogenesis

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

catabolic process [inference]

collagen catabolic process

collagen metabolic process [inference]

collagen catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

extracellular matrix disassembly

extracellular structure organization [inference]

extracellular matrix organization

extracellular matrix disassembly

external encapsulating structure organization [inference]

extracellular matrix organization

extracellular matrix disassembly

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

bone morphogenesis

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202
extracellular matrix	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

external encapsulating structure [inference]

extracellular matrix

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endopeptidase activity
metalloendopeptidase activity	IEA	22301074 30032202
calcium ion binding
collagen binding
zinc ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

collagen binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

matrix metalloproteinase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
collagen catabolic process
extracellular matrix organization
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis
zinc ion binding

Displaying entries **1 - 10** of 12 in total

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InterPro
Hemopexin, conserved site
Hemopexin-like domain superfamily
Hemopexin-like domain
Hemopexin-like repeats
Metallopeptidase, catalytic domain superfamily
PGBD-like superfamily
Peptidase M10, metallopeptidase
Peptidase M10A, catalytic domain
Peptidase M10A, cysteine switch, zinc binding site
Peptidase M10A

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	4322	HUMAN09039
Mus musculus	17386	MOUSE64508
Rattus norvegicus	171052	RATNO40397
Bos taurus	281914	BOVIN06328
Sus scrofa	397346	PIGXX35284
Canis lupus familiaris	403763	CANLF15346
Pan troglodytes	451513	PANTR04187
Felis catus	493679	FELCA23670
Macaca mulatta	703980	MACMU10476
Danio rerio	100006896	DANRE08990