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sphingomyelin synthase 1

Summary

Gene Symbol

SGMS1

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 100037303
KEGG Gene ID: ssc:100037303
PubChem: 100037303

Annotation

Keyword

Apoptosis
Golgi apparatus
Kinase
Phosphoprotein
Reference proteome
Sphingolipid metabolism
Transferase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A4X1V2J2	Sphingomyelin synthase 1
A0AAS4	Sphingomyelin synthase 1
A0A8D0IC26	Sphingomyelin synthase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
sphingomyelin biosynthetic process	IEA	30032202
ceramide biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

amide metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

amide biosynthetic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process [inference]

ceramide biosynthetic process

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

sphingolipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

phospholipid metabolic process [inference]

sphingomyelin metabolic process [inference]

sphingomyelin biosynthetic process

phospholipid biosynthetic process [inference]

sphingomyelin biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
Golgi membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ceramide cholinephosphotransferase activity	IEA	30032202
protein binding	IEA	22301074
sphingomyelin synthase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups [inference]

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K04714

Name

shingomyelin synthase [EC:2.7.8.27]

References

Rhea

an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine

a sphingomyelin + a 1,2-diacyl-sn-glycerol

Enzyme

2.7.8.27

PMID

Ortholog

Displaying entries **41 - 50** of 98 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Ailuropoda melanoleuca	100468555		AILME17671
Mustela putorius furo	101689257		MUSPF08491
Felis catus	101090897		FELCA26404
Panthera leo	122202729		PANLE03794
Tursiops truncatus	101329524		TURTR01231
Balaenoptera musculus	118883069		BALMU15284
Loxodonta africana	100662186		LOXAF15642
Equus caballus	100062484		HORSE16314
Bos taurus	533538		BOVIN21115
Capra hircus	102184583		CAPHI18026

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024