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sodium voltage-gated channel alpha subunit 4

Summary

Gene Symbol

SCN4A

Organism

Equus caballus (horse)

External Links

NCBI Gene: 100049793
PubChem: 100049793

Annotation

Keyword

Cell membrane
Coiled coil
Disease variant
Disulfide bond
Glycoprotein
Phosphoprotein
Reference proteome
Repeat
Sodium channel
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q28371	Sodium channel protein skeletal muscle subunit alpha Sodium channel protein type IV subunit alpha Voltage-gated sodium channel subunit alpha Nav1.4
F7CKF4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
neuronal action potential	IEA	30032202
sodium ion transmembrane transport	IEA	30032202
cardiac muscle cell action potential involved in contraction
membrane depolarization during action potential	IEA	30032202
regulation of skeletal muscle contraction by action potential

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of striated muscle contraction [inference]

regulation of skeletal muscle contraction [inference]

regulation of skeletal muscle contraction by action potential

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential [inference]

neuronal action potential

cardiac muscle cell action potential [inference]

cardiac muscle cell action potential involved in contraction

regulation of skeletal muscle contraction by action potential

membrane depolarization [inference]

membrane depolarization during action potential

Displaying **all 3** entries
GO Term	Evidence Code	PMID
voltage-gated sodium channel complex	IEA	22301074 30032202
plasma membrane	IEA	30032202
axon	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated sodium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying **all 2** entries
GO Term	Evidence Code	PMID
voltage-gated sodium channel activity	IEA	22301074 30032202
protein binding	IEA	22301074

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

sodium channel activity [inference]

voltage-gated sodium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

sodium channel activity [inference]

voltage-gated sodium channel activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

voltage-gated sodium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

voltage-gated sodium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

sodium channel activity [inference]

voltage-gated sodium channel activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

voltage-gated sodium channel activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 60 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	6329	HUMAN35667
Rattus norvegicus	25722	RATNO01336
Mus musculus	110880	MOUSE06123
Bos taurus	517426	BOVIN13644
Macaca mulatta	718194	MACMU16267
Monodelphis domestica	100026330	MONDO10159
Ornithorhynchus anatinus	100092342	ORNAN03346
Taeniopygia guttata	100224584	TAEGU15480
Oryctolagus cuniculus	100350524	RABIT07876
Callithrix jacchus	100414137	CALJA36685