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4-hydroxy-2-oxoglutarate aldolase 1

Summary

Gene Symbol

HOGA1

Organism

Equus caballus (horse)

External Links

NCBI Gene: 100070689
KEGG Gene ID: ecb:100070689
PubChem: 100070689

Annotation

Keyword

Lyase
Proteomics identification
Reference proteome
Schiff base

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A9L0RSD9	Dihydrodipicolinate synthase-like Probable 2-keto-4-hydroxyglutarate aldolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
N-acetylneuraminate catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
4-hydroxy-tetrahydrodipicolinate synthase activity	IEA	30032202
N-acetylneuraminate lyase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

oxo-acid-lyase activity [inference]

N-acetylneuraminate lyase activity

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

4-hydroxy-tetrahydrodipicolinate synthase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K18123

Name

4-hydroxy-2-oxoglutarate aldolase [EC:4.1.3.16]

References

21998747

Rhea

(4R)-4-hydroxy-2-oxoglutarate

pyruvate + glyoxylate

Enzyme

4.1.3.16

PMID

5780845

(4S)-4-hydroxy-2-oxoglutarate

pyruvate + glyoxylate

Enzyme

PMID

Ortholog

Displaying entries **41 - 50** of 91 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mustela putorius furo	101693912		MUSPF14759
Felis catus	101101417		FELCA27369
Panthera leo	122202319		PANLE02959
Balaenoptera musculus	118882584		BALMU15145
Loxodonta africana	100670230		LOXAF15549
Sus scrofa	100153961		PIGXX08279
Bos taurus	506001		BOVIN21295
Capra hircus	102173994		CAPHI17888
Ovis aries	101114573		SHEEP11495
Oryctolagus cuniculus	100344505		RABIT06902

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024