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phosphate cytidylyltransferase 1A, choline

Summary

Gene Symbol

PCYT1A

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 100125779
KEGG Gene ID: bta:100125779
PubChem: 100125779

Annotation

Keyword

Coiled coil
Phospholipid biosynthesis
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2KIR5
A0A3Q1M4Q5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
CDP-choline pathway	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organonitrogen compound metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process [inference]

CDP-choline pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
phosphatidylcholine binding	IEA	30032202
choline-phosphate cytidylyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

cytidylyltransferase activity [inference]

choline-phosphate cytidylyltransferase activity

binding [inference]

lipid binding [inference]

phospholipid binding [inference]

phosphatidylcholine binding

ion binding [inference]

cation binding [inference]

phosphatidylcholine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CYTIDYLYLTRANSFERASE

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 6** entries
Gene Ontology
CDP-choline pathway
catalytic activity
choline-phosphate cytidylyltransferase activity
lipid metabolic process
phosphatidylcholine binding
phospholipid biosynthetic process

Displaying **all 4** entries
InterPro
CTP
Choline-phosphate cytidylyltransferase Pcy1-like
Cytidyltransferase-like domain
Rossmann-like alpha/beta/alpha sandwich fold

KEGG BRITE Database

Orthology

K00968

Name

choline-phosphate cytidylyltransferase [EC:2.7.7.15]

References

7918629

Rhea

H⁺ + phosphocholine + CTP

diphosphate + CDP-choline

Enzyme

2.7.7.15

PMID

Ortholog

Displaying entries **41 - 50** of **100** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Vicugna pacos	102534645	30538_0:00025b		VICPA05163
Physeter catodon	102986176	9755_0:000137
Astyanax mexicanus	103031553			ASTMX09200
Astyanax mexicanus	103040438			ASTMX06450
Callorhinchus milii	103190455			CALMI43758
Ursus maritimus	103678938			URSMA29416
Nannospalax galili	103738517			NANGA17719
Rhinopithecus roxellana	104676385			RHIRO18851
Bison bison bison	104984541	43346_0:000e6b
Camelus bactrianus	105072395	9837_0:0029c0

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024