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acyl-CoA synthetase long chain family member 1

Summary

Gene Symbol

Acsl1

Organism

Cavia porcellus (domestic guinea pig)

External Links

NCBI Gene: 100135469
PubChem: 100135469

Annotation

Keyword

ATP-binding
Acetylation
Fatty acid metabolism
Glycoprotein
Ligase
Magnesium
Microsome
Mitochondrion outer membrane
Nitration
Peroxisome
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2C9F1D9	Acyl-CoA synthetase Long-chain acyl-CoA synthetase
Q9JID6	Arachidonate--CoA ligase Long-chain acyl-CoA synthetase 1 Palmitoyl-CoA ligase Phytanate--CoA ligase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
very long-chain fatty acid metabolic process
long-chain fatty acid metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
mitochondrial outer membrane
peroxisomal membrane
endoplasmic reticulum	IEA	30032202
endoplasmic reticulum membrane
membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
long-chain fatty acid-CoA ligase activity	IEA	22301074 30032202
ATP binding
arachidonate-CoA ligase activity
phytanate-CoA ligase activity
pristanate-CoA ligase activity

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-sulfur bonds [inference]

CoA-ligase activity [inference]

long-chain fatty acid-CoA ligase activity

arachidonate-CoA ligase activity

acid-thiol ligase activity [inference]

fatty acid ligase activity [inference]

long-chain fatty acid-CoA ligase activity

arachidonate-CoA ligase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

fatty acid ligase activity [inference]

long-chain fatty acid-CoA ligase activity

arachidonate-CoA ligase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

long chain acyl-coA synthetase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
fatty acid metabolic process
ligase activity

Displaying **all 3** entries
InterPro
AMP-binding, conserved site
AMP-dependent synthetase/ligase domain
ANL, N-terminal domain

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	2180	HUMAN78308
Mus musculus	14081	MOUSE58001
Rattus norvegicus	25288	RATNO10758
Sus scrofa	448982	PIGXX09085
Pan troglodytes	461631	PANTR34893
Canis lupus familiaris	475631	CANLF04784
Bos taurus	537161	BOVIN21924
Danio rerio	555308	DANRE16668
Macaca mulatta	694871	MACMU36173
Monodelphis domestica	100012070	MONDO25978