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chemokine (C-C motif) ligand 2

Summary

Gene Symbol

Ccl2

Organism

Cavia porcellus (domestic guinea pig)

External Links

NCBI Gene: 100135494
PubChem: 100135494

Annotation

Keyword

Chemotaxis
Cytokine
Disulfide bond
Glycoprotein
Inflammatory response
Pyrrolidone carboxylic acid
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q08782	Monocyte chemoattractant protein 1 Monocyte chemotactic protein 1 Small-inducible cytokine A2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
inflammatory response
immune response	IEA	22301074
sensory perception of pain
eosinophil chemotaxis	IEA	30032202
positive regulation of synaptic transmission, glutamatergic

GO Hierarchy

biological process

immune system process [inference]

immune response

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

eosinophil migration [inference]

eosinophil chemotaxis

cellular process [inference]

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

myeloid leukocyte migration [inference]

granulocyte migration [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

eosinophil migration [inference]

eosinophil chemotaxis

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis [inference]

leukocyte chemotaxis [inference]

granulocyte chemotaxis [inference]

eosinophil chemotaxis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, glutamatergic

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, glutamatergic

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074
extracellular space

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
chemokine activity	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

G protein-coupled receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

cytokine receptor binding [inference]

chemokine receptor binding [inference]

chemokine activity

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity [inference]

chemokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

C-C motif chemokine 2

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cell chemotaxis
chemokine activity
cytokine activity
eosinophil chemotaxis
immune response

Displaying **all 3** entries
InterPro
Chemokine beta/gamma/delta
Chemokine interleukin-8-like domain
Chemokine interleukin-8-like superfamily

Ortholog

Displaying entries **1 - 10** of 25 in total

1

2

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Species	Gene ID	Orthologous MAtrix
Mus musculus	20292	MOUSE05366
Mus musculus	20293	MOUSE05368
Mus musculus	20296	MOUSE05361
Mus musculus	20306	MOUSE05362
Mus musculus	20307	MOUSE05369
Rattus norvegicus	24770	RATNO02716
Rattus norvegicus	29397	RATNO02463
Rattus norvegicus	287561	RATNO02457
Rattus norvegicus	287562	RATNO02493
Cricetulus griseus	100763261	CRIGR01155

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