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MIRAGE
acetyl-CoA acyltransferase 2

Summary
Gene Symbol
  • ACAA2
Organism
Pongo abelii (Sumatran orangutan)
NCBI Gene
100171644
KEGG Gene ID
pon:100171644
PubChem
100171644
Annotation
Keyword
  • Acetylation
  • Acyltransferase
  • Fatty acid metabolism
  • Hydrolase
  • Mitochondrion
  • Phosphoprotein
  • Reference proteome
  • Transit peptide
Proteins
Displaying 1 entry
UniProt Protein Name
Q5RES5
  • Acetyl-CoA acetyltransferase
  • Acetyl-CoA acyltransferase
  • Acyl-CoA hydrolase, mitochondrial
  • Beta-ketothiolase
  • Mitochondrial 3-oxoacyl-CoA thiolase
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
acetyl-CoA acetyltransferase
Functional Category
  • I: Lipid transport and metabolism
  • T: Signal transduction mechanisms
  • V: Defense mechanisms
Displaying all 3 entries
Gene Ontology
acyltransferase activity, transferring groups other than amino-acyl groups
fatty acid beta-oxidation
transferase activity
Displaying all 7 entries
InterPro
Thiolase, C-terminal
Thiolase, N-terminal
Thiolase, active site
Thiolase, acyl-enzyme intermediate active site
Thiolase, conserved site
Thiolase-like
Thiolase
KEGG BRITE Database
Orthology
K07508
Name
acetyl-CoA acyltransferase 2 [EC:2.3.1.16]
References
Rhea

RHEA:20289

H2O + acetyl-CoA
H+ + acetate + CoA
Enzyme
PMID

RHEA:16645

H2O + hexadecanoyl-CoA
H+ + CoA + hexadecanoate
Enzyme
PMID

RHEA:21036

acetyl-CoA
acetoacetyl-CoA + CoA
Enzyme
PMID

RHEA:21564

acetyl-CoA + an acyl-CoA
CoA + a 3-oxoacyl-CoA
Enzyme
PMID
Ortholog
Displaying entries 11 - 20 of 81 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
100304819 ICTPU29385
100312959 PIGXX14047
100339733 RABIT13200
100402284 CALJA08350
100476344 AILME03989
100595632 NOMLE29697
100669834 LOXAF18457
100699406 ORENI10558
100715434 CAVPO08147
100765829 CRIGR14584
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025