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glyoxylate and hydroxypyruvate reductase

Summary

Gene Symbol

GRHPR

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100171680
KEGG Gene ID: pon:100171680
PubChem: 100171680

Annotation

Keyword

Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5REL8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycerate dehydrogenase activity	IEA	30032202
hydroxypyruvate reductase activity	IEA	30032202
glyoxylate reductase (NADP+) activity	IEA	30032202
NAD binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

glyoxylate reductase activity [inference]

glyoxylate reductase (NADP+) activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dehydrogenase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity

Displaying **all 3** entries
InterPro
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NAD(P)-binding domain superfamily

KEGG BRITE Database

Orthology

K00049

Name

glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81]

References

16756993

Ortholog

Displaying entries **1 - 10** of 58 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	9380	HUMAN97039
Mus musculus	76238	MOUSE42961
Pan troglodytes	465099	PANTR43997
Danio rerio	497183	DANRE06801
Bos taurus	504764	BOVIN34595
Canis lupus familiaris	612041	CANLF02322
Macaca mulatta	694185	MACMU12604
Monodelphis domestica	100018478	MONDO30778
Sus scrofa	100154014	PIGXX15745
Ciona intestinalis	100178763	CIOIN03389