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macrophage expressed 1

Summary

Gene Symbol

MPEG1

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100172369
PubChem: 100172369

Annotation

Keyword

Adaptive immunity
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Innate immunity
Reference proteome
Signal
Transmembrane beta strand
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5RBP9	Perforin-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
antigen processing and presentation of exogenous peptide antigen
defense response to Gram-negative bacterium
adaptive immune response
defense response to Gram-positive bacterium
antigen processing and presentation of exogenous peptide antigen via MHC class I

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

innate immune response [inference]

antibacterial innate immune response

antigen processing and presentation [inference]

dendritic cell antigen processing and presentation

antigen processing and presentation of exogenous antigen [inference]

antigen processing and presentation of exogenous peptide antigen

antigen processing and presentation of exogenous peptide antigen via MHC class I

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class I [inference]

antigen processing and presentation of exogenous peptide antigen via MHC class I

antigen processing and presentation of exogenous peptide antigen

antigen processing and presentation of exogenous peptide antigen via MHC class I

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

immune response [inference]

adaptive immune response

innate immune response [inference]

antibacterial innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

antibacterial innate immune response

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasmic vesicle
phagolysosome membrane
phagocytic vesicle
phagocytic vesicle membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

phagolysosome membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

phagolysosome membrane

endocytic vesicle membrane [inference]

phagocytic vesicle membrane

phagolysosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endocytic vesicle [inference]

phagocytic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endocytic vesicle [inference]

phagocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endocytic vesicle [inference]

phagocytic vesicle

Displaying 1 entry
GO Term	Evidence Code	PMID
wide pore channel activity

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

passive transmembrane transporter activity [inference]

channel activity [inference]

wide pore channel activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

macrophage expressed 1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
adaptive immune response

Displaying **all 2** entries
InterPro
Macrophage-expressed gene 1 protein
Membrane attack complex component/perforin (MACPF) domain

Ortholog

Displaying entries **1 - 10** of 86 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Mus musculus	17476		MOUSE26332
Rattus norvegicus	64552		RATNO19777
Homo sapiens	219972	9606_1:002dc0	HUMAN06204
Danio rerio	335407		DANRE42735
Pan troglodytes	451211	9598_0:0032dd	PANTR02982
Canis lupus familiaris	475960		CANLF05690
Danio rerio	553612		DANRE42757
Macaca mulatta	700274		MACMU09264
Danio rerio	795504		DANRE42661
Equus caballus	100066669		HORSE05807