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solute carrier family 39 member 6

Summary

Gene Symbol

SLC39A6

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100172832
PubChem: 100172832

Annotation

Keyword

Cell membrane
Cell projection
Coiled coil
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix
Zinc transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5R9M9	Solute carrier family 39 member 6 Zrt- and Irt-like protein 6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
epithelial to mesenchymal transition
intracellular monoatomic cation homeostasis	IEA	30032202
lymphocyte activation
T cell receptor signaling pathway
zinc ion transmembrane transport

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

leukocyte activation [inference]

lymphocyte activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

zinc ion transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

antigen receptor-mediated signaling pathway [inference]

T cell receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
apical plasma membrane
lamellipodium membrane
membrane raft

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

lamellipodium membrane

membrane microdomain [inference]

membrane raft

leading edge membrane [inference]

lamellipodium membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
zinc ion transmembrane transporter activity	IEA	30032202
monoatomic cation:bicarbonate symporter activity	IEA	30032202

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity [inference]

monoatomic cation:bicarbonate symporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity [inference]

monoatomic cation:bicarbonate symporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

salt transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

bicarbonate transmembrane transporter activity [inference]

monoatomic cation:bicarbonate symporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
metal ion transmembrane transporter activity
zinc ion transmembrane transporter activity

Displaying 1 entry
InterPro
Zinc/iron permease

Ortholog

Displaying entry **81 - 81** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Ursus americanus	123779591		URSAM23365

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyTouCan

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements