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ER lipid raft associated 2

Summary

Gene Symbol

ERLIN2

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100173353
PubChem: 100173353

Annotation

Keyword

Acetylation
Cholesterol metabolism
Endoplasmic reticulum
Glycoprotein
Reference proteome
Signal
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A2J8TPB0	Endoplasmic reticulum lipid raft-associated protein Stomatin-prohibitin-flotillin-HflC/K domain-containing protein
Q5R7C5	Endoplasmic reticulum lipid raft-associated protein 2 Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
A0A2J8TPC1	Endoplasmic reticulum lipid raft-associated protein Stomatin-prohibitin-flotillin-HflC/K domain-containing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol metabolic process
SREBP signaling pathway	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

signal transduction [inference]

ER-nucleus signaling pathway [inference]

SREBP signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

response to stimulus [inference]

response to stress [inference]

response to sterol depletion [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to sterol depletion [inference]

SREBP signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

ER-nucleus signaling pathway [inference]

SREBP signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
endoplasmic reticulum	IEA	22301074 30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cholesterol binding	IEA	30032202
ubiquitin protein ligase binding	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

small molecule binding [inference]

alcohol binding [inference]

cholesterol binding

organic cyclic compound binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cholesterol binding
ubiquitin protein ligase binding

Displaying **all 3** entries
InterPro
Band 7 domain
Band 7/SPFH domain superfamily
Erlin1/2

Ortholog

Displaying entries **11 - 20** of 86 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Callithrix jacchus	100414568		CALJA08984
Ailuropoda melanoleuca	100468740		AILME14819
Loxodonta africana	100675103		LOXAF12234
Oreochromis niloticus	100709255		ORENI09766
Cavia porcellus	100734771		CAVPO22667
Cricetulus griseus	100770510		CRIGR04432
Sarcophilus harrisii	100916340		SARHA14287
Otolemur garnettii	100966699		OTOGA06529
Pan paniscus	100994817	9597_0:002589	PANPA38041
Saimiri boliviensis boliviensis	101054112		SAIBB29517