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sphingosine-1-phosphate lyase 1

Summary

Gene Symbol

SGPL1

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100173995
KEGG Gene ID: pon:100173995
PubChem: 100173995

Annotation

Keyword

Acetylation
Apoptosis
Endoplasmic reticulum
Lyase
Nitration
Phosphoprotein
Pyridoxal phosphate
Reference proteome
Signal-anchor
Sphingolipid metabolism
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A663DEX8	Sphingosine-1-phosphate aldolase
Q5R4G0	Sphingosine-1-phosphate aldolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
carboxylic acid metabolic process	IEA	22301074
sphingolipid catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

organonitrogen compound catabolic process [inference]

sphingolipid catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid catabolic process

membrane lipid catabolic process [inference]

sphingolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

sphingolipid catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
pyridoxal phosphate binding	IEA	22301074
sphinganine-1-phosphate aldolase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

aldehyde-lyase activity [inference]

sphinganine-1-phosphate aldolase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01634

Name

sphinganine-1-phosphate aldolase [EC:4.1.2.27]

References

11018465

Rhea

RHEA:18593

sphinganine 1-phosphate

hexadecanal + phosphoethanolamine

Enzyme

4.1.2.27

PMID

RHEA:33507

sphing-4-enine 1-phosphate

(2E)-hexadecenal + phosphoethanolamine

Enzyme

4.1.2.27

PMID

Ortholog

Displaying entries **81 - 83** of 83 in total

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Species	Gene ID	Orthologous MAtrix
Corvus moneduloides	116447138	CORMO25764
Carlito syrichta	103253897	CARSF29218
Strigops habroptila	115608440	STRHB03885

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024

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