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cadherin 1

Summary

Gene Symbol

CDH1

Organism

Pongo abelii (Sumatran orangutan)

External Links

NCBI Gene: 100174439
PubChem: 100174439

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Cytoplasm
Disulfide bond
Endosome
Glycoprotein
Golgi apparatus
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5RAX1	Epithelial cadherin Uvomorulin

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
regulation of gene expression
homophilic cell adhesion via plasma membrane adhesion molecules	IEA	22301074
multicellular organism development	IEA	30032202
cell-cell junction assembly	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction organization [inference]

synapse organization [inference]

synapse assembly

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

anatomical structure development [inference]

multicellular organism development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
plasma membrane	IEA	22301074
endosome
adherens junction	IEA	30032202
cell-cell junction
catenin complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA	22301074 30032202
cadherin binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
adherens junction organization
cadherin binding
calcium ion binding
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell-cell adhesion mediated by cadherin
cell-cell junction assembly
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 6** entries
InterPro
Cadherin conserved site
Cadherin, Y-type LIR-motif
Cadherin-like superfamily
Cadherin-like
Cadherin
Catenin binding domain superfamily

Ortholog

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	999	9606_1:003d80
Mus musculus	12550		MOUSE57774
Rattus norvegicus	83502		RATNO14841
Bos taurus	282637		BOVIN10689
Canis lupus familiaris	442858		CANLF16015
Pan troglodytes	468009	9598_0:00403b	PANTR12691
Macaca mulatta	704387		MACMU26370
Monodelphis domestica	100027800		MONDO03590
Sus scrofa	100048953		PIGXX27191
Ornithorhynchus anatinus	100079609		ORNAN03463