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hydroxyacylglutathione hydrolase

Summary

Gene Symbol

HAGH

Organism

Taeniopygia guttata (zebra finch)

External Links

NCBI Gene: 100190196
KEGG Gene ID: tgu:100190196
PubChem: 100190196

Annotation

Keyword

Hydrolase
Metal-binding
Mitochondrion
Transit peptide
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
B5FYT6	Glyoxalase II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IEA	22301074
glutathione metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

small molecule catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

glutathione metabolic process

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic substance catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic hydroxy compound metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

lactate metabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular ketone metabolic process [inference]

methylglyoxal metabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

cellular catabolic process [inference]

ketone catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

aldehyde catabolic process [inference]

methylglyoxal catabolic process [inference]

methylglyoxal catabolic process to lactate [inference]

methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
hydroxyacylglutathione hydrolase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

thiolester hydrolase activity [inference]

hydroxyacylglutathione hydrolase activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

H₂O + (R)-S-lactoylglutathione

H⁺ + (R)-lactate + glutathione

Enzyme

3.1.2.6

PMID

H₂O + an S-(2-hydroxyacyl)glutathione

H⁺ + glutathione + a 2-hydroxy carboxylate

Enzyme

3.1.2.6

PMID

Ortholog

Displaying entries **41 - 50** of 59 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Chinchilla lanigera	102017279		CHILA11511
Aotus nancymaae	105709796		AOTNA20902
Phascolarctos cinereus	110221856		PHACI20022
Saimiri boliviensis boliviensis	101032198		SAIBB14150
Ictidomys tridecemlineatus	101971748		ICTTR07827
Myotis lucifugus	102419338		MYOLU13148
Rhinolophus ferrumequinum	117019470		RHIFE32904
Chlorocebus sabaeus	103226359		CHLSB14303
Rhinopithecus bieti	108519390		RHIBE24169
Nomascus leucogenys	100599375		NOMLE14416

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024