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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
polycystic kidney disease 2
Summary
- Gene Symbol
-
- pkd2
- Organism
- Oryzias latipes (Japanese medaka)
Annotation
- Keyword
-
- Alternative splicing
- Calcium channel
- Cell membrane
- Cilium
- Coiled coil
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Metal-binding
- Phosphoprotein
- Potassium channel
- Reference proteome
- Repeat
- Transmembrane helix
- Voltage-gated channel
- Wnt signaling pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| H2LRU7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| inorganic cation transmembrane transport |
|
|
| cellular response to calcium ion |
|
|
| calcium ion transmembrane transport |
|
|
| cell surface receptor signaling pathway |
|
|
| detection of mechanical stimulus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| cytoplasmic vesicle membrane |
|
|
| endoplasmic reticulum membrane |
|
|
| plasma membrane |
|
|
| ciliary membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| voltage-gated sodium channel activity | ||
| calcium channel activity |
|
|
| muscle alpha-actinin binding | ||
| voltage-gated calcium channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Polycystic kidney disease
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium channel activity |
| calcium ion binding |
| detection of mechanical stimulus |
| InterPro |
|---|
| Polycystic kidney disease type 2 protein |
| Polycystin cation channel, PKD1/PKD2 |
| Polycystin domain |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5311 | HUMAN76511 | |||
| 18764 | MOUSE43586 | |||
| 432387 | 7955_0:000174 | DANRE17787 | ||
| 461367 | PANTR34093 | |||
| 498328 | RATNO08534 | |||
| 702179 | MACMU36998 | |||
| 100016662 | MONDO27201 | |||
| 100063439 | HORSE30629 | |||
| 100219153 | TAEGU23358 | |||
| 100411856 | CALJA29362 |
