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agrin

Summary

Gene Symbol

AGRN

Organism

Taeniopygia guttata (zebra finch)

External Links

NCBI Gene: 100219336
KEGG Gene ID: tgu:100219336
PubChem: 100219336

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
receptor clustering	IEA	22301074
G protein-coupled acetylcholine receptor signaling pathway	IEA	22301074
multicellular organism development	IEA	30032202
central nervous system development	IEA	30032202
negative regulation of serine-type peptidase activity	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

cellular developmental process [inference]

cell differentiation

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure development [inference]

multicellular organism development

system development [inference]

central nervous system development

cellular developmental process [inference]

cell differentiation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of serine-type peptidase activity [inference]

negative regulation of serine-type peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of serine-type peptidase activity [inference]

negative regulation of serine-type peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of serine-type peptidase activity [inference]

negative regulation of serine-type peptidase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of serine-type peptidase activity

regulation of serine-type peptidase activity [inference]

negative regulation of serine-type peptidase activity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
serine-type endopeptidase inhibitor activity	IEA	30032202
calcium ion binding	IEA	22301074
laminin binding	IEA	22301074

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

laminin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

extracellular matrix binding [inference]

laminin binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

serine-type endopeptidase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

agrin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
receptor clustering

Displaying **all 3** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
EGF-like domain
Laminin G domain

KEGG BRITE Database

Orthology

K06254

Name

agrin

References

Ortholog

Displaying entries **21 - 30** of **104** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Jaculus jaculus	101612657		JACJA09189
Mustela putorius furo	101686006		MUSPF00945
Ficedula albicollis	101817826	59894_0:002e31
Chrysemys picta bellii	101941018		CHRPI32806
Geospiza fortis	102044088	48883_0:00291f
Zonotrichia albicollis	102061409	44394_0:003101
Pseudopodoces humilis	102109265	181119_0:002e4e
Capra hircus	102169403		CAPHI07001
Callorhinchus milii	103187444		CALMI36764
Chlorocebus sabaeus	103225827		CHLSB09519