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Standards Ontologies Notations
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Summary
Gene Symbol
  • ST8SIA1
Organism
Oryctolagus cuniculus (rabbit)
NCBI Gene
100351155
KEGG Gene ID
ocu:100351155
PubChem
100351155
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Sphingolipid metabolism
  • Transferase
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
G1T4S8
  • Alpha-2,8-sialyltransferase 8A
  • Ganglioside GD3 synthase
  • Sialyltransferase 8A
  • Sialyltransferase St8Sia I
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 3 entries
GO Term Evidence Code PMID
protein glycosylation
oligosaccharide metabolic process
N-glycan processing
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K03371
Name
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.3.8]
References
Reactions
Displaying all 4 entries
KEGG Reaction Enzyme Acceptor Product
R13175
R06032
R05947
R05940
Rhea

RHEA:19313

an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Ortholog
Displaying entries 81 - 90 of 94 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
117714671 61156_0:002aba
118144189 CALJA46527
118287693 SCOMX21224
118579167 38674_0:001144
118902638 BALMU03311
119808271 1047088_0:000a16
121147775 130825_0:0007d4
122224343 PANLE17723
125342728 214514_0:004c43
125399205 447135_0:000c34
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024