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5-hydroxytryptamine receptor 1E

Summary

Gene Symbol

Htr1e

Organism

Cavia porcellus (domestic guinea pig)

External Links

NCBI Gene: 100379275
PubChem: 100379275

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6VB83	Serotonin receptor 1E

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IEA	30032202
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway	IEA	30032202
chemical synaptic transmission	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

adenylate cyclase-inhibiting serotonin receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway [inference]

adenylate cyclase-inhibiting serotonin receptor signaling pathway

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

adenylate cyclase-inhibiting serotonin receptor signaling pathway

G protein-coupled serotonin receptor signaling pathway [inference]

adenylate cyclase-inhibiting serotonin receptor signaling pathway

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	22301074 30032202
dendrite	IEA	30032202
synapse

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying **all 2** entries
GO Term	Evidence Code	PMID
G protein-coupled serotonin receptor activity	IEA	22301074 30032202
neurotransmitter receptor activity	IEA	30032202

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled amine receptor activity [inference]

G protein-coupled serotonin receptor activity

neurotransmitter receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

receptor

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
adenylate cyclase-activating adrenergic receptor signaling pathway

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	3354	HUMAN85690
Pan troglodytes	472064	PANTR38657
Canis lupus familiaris	481907	CANLF02963
Bos taurus	616356	BOVIN35729
Macaca mulatta	697598	MACMU34569
Monodelphis domestica	100025139	MONDO15012
Equus caballus	100065574	HORSE00838
Ornithorhynchus anatinus	100082532	ORNAN10771
Pongo abelii	100461112	PONAB32191
Ailuropoda melanoleuca	100480441	AILME07130