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isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

Summary

Gene Symbol

IDH3A

Organism

Callithrix jacchus (white-tufted-ear marmoset)

External Links

NCBI Gene: 100413152
KEGG Gene ID: cjc:100413152
PubChem: 100413152

Annotation

Keyword

Magnesium
Metal-binding
Mitochondrion
Reference proteome
Transit peptide
Tricarboxylic acid cycle

Proteins

Displaying 1 entry
UniProt	Protein Name
U3E4Q8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
isocitrate metabolic process	IEA	30032202
tricarboxylic acid cycle	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

isocitrate metabolic process

primary metabolic process [inference]

tricarboxylic acid cycle

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

isocitrate metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

isocitrate metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

isocitrate metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

isocitrate metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

tricarboxylic acid metabolic process [inference]

isocitrate metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
NAD binding	IEA	22301074
magnesium ion binding	IEA	22301074
isocitrate dehydrogenase (NAD+) activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

isocitrate dehydrogenase [NAD(P)+] activity [inference]

isocitrate dehydrogenase (NAD+) activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

isocitrate dehydrogenase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
isocitrate dehydrogenase (NAD+) activity
isocitrate metabolic process
magnesium ion binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
tricarboxylic acid cycle

Displaying **all 3** entries
InterPro
Isocitrate dehydrogenase NAD-dependent
Isocitrate/isopropylmalate dehydrogenase, conserved site
Isopropylmalate dehydrogenase-like domain

KEGG BRITE Database

Orthology

K00030

Name

isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]

References

10601238

Ortholog

Displaying entries **21 - 30** of 91 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Cavia porcellus	100720114			CAVPO21803
Cricetulus griseus	100754480			CRIGR03982
Otolemur garnettii	100943826	30611_0:000bf5		OTOGA16546
Pan paniscus	100987648			PANPA13895
Saimiri boliviensis boliviensis	101050203			SAIBB37413
Takifugu rubripes	101068530			TAKRU51703
Felis catus	101085721			FELCA13036
Ovis aries	101120868			SHEEP07816
Gorilla gorilla gorilla	101135027			GORGO09434
Tursiops truncatus	101321334			TURTR11072

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024