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gamma-glutamyltransferase 5

Summary

Gene Symbol

GGT5

Organism

Ailuropoda melanoleuca (giant panda)

External Links

NCBI Gene: 100477159
KEGG Gene ID: aml:100477159
PubChem: 100477159

Annotation

Keyword

Acyltransferase
Hydrolase
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
G1M5J8	Gamma-glutamyltransferase Gamma-glutamyltranspeptidase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glutathione catabolic process	IEA	22301074 30032202
inflammatory response	IEA	30032202
leukotriene D4 biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

catabolic process [inference]

organic substance catabolic process [inference]

glutathione catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

sulfur compound biosynthetic process [inference]

leukotriene D4 biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

sulfur compound metabolic process [inference]

sulfur compound biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

sulfur compound biosynthetic process [inference]

leukotriene D4 biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

fatty acid derivative metabolic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

fatty acid derivative metabolic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

glutathione metabolic process [inference]

glutathione catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

organic substance catabolic process [inference]

glutathione catabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid derivative biosynthetic process [inference]

leukotriene D4 biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

sulfur compound metabolic process [inference]

sulfur compound biosynthetic process [inference]

leukotriene D4 biosynthetic process

leukotriene D4 metabolic process [inference]

leukotriene D4 biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process [inference]

leukotriene D4 biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

leukotriene D4 biosynthetic process

sulfur compound biosynthetic process [inference]

leukotriene D4 biosynthetic process

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
leukotriene-C(4) hydrolase	IEA	30032202
glutathione hydrolase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

omega peptidase activity [inference]

threonine-type peptidase activity [inference]

glutathione hydrolase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

omega peptidase activity [inference]

threonine-type peptidase activity [inference]

glutathione hydrolase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Gamma-glutamyltranspeptidase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
glutathione catabolic process
glutathione hydrolase activity
hydrolase activity
transferase activity

Displaying **all 4** entries
InterPro
Gamma-glutamyltranspeptidase, large subunit, C-terminal domain
Gamma-glutamyltranspeptidase, small subunit
Gamma-glutamyltranspeptidase
Nucleophile aminohydrolases, N-terminal

KEGG BRITE Database

Orthology

K18592

Name

gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]

References

Rhea

H₂O + an S-substituted glutathione

an S-substituted L-cysteinylglycine + L-glutamate

Enzyme

3.4.19.13

PMID

an α-amino acid

5-L-glutamyl amino acid

Enzyme

2.3.2.2

PMID

H₂O + glutathione

L-glutamate + L-cysteinylglycine

Enzyme

3.4.19.13

PMID

Ortholog

Displaying entries **111 - 120** of **122** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Leopardus geoffroyi	123587556	46844_0:0040ab
Ursus americanus	123795615	9643_0:0023ce		URSAM00103
Mirounga angustirostris	123852864	9716_0:001e9d
Meles meles	123954520	9662_0:0032b5
Lynx rufus	124518274	61384_0:002401
Lutra lutra	125082413	9657_0:003872
Prionailurus viverrinus	125149358	61388_0:003539
Panthera uncia	125914026	29064_0:0043d0
Nyctereutes procyonoides	129507694	34880_0:00149e
Neofelis nebulosa	131489140	61452_0:003612

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024