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Standards Ontologies Notations
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

Summary
Gene Symbol
  • st6gal1
Organism
Xenopus tropicalis (tropical clawed frog)
NCBI Gene
100491268
KEGG Gene ID
xtr:100491268
PubChem
100491268
Alliance of Genome Resources
Annotation
Keyword
  • Coiled coil
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
E4ZFH6
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Sialyltransferase
Functional Category
  • H: Coenzyme transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
sialyltransferase activity
transferase activity
Displaying all 2 entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29
KEGG BRITE Database
Orthology
K00778
Name
beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.3.1]
References
Reactions
Displaying 1 entry
KEGG Reaction Enzyme Acceptor Product
R05990
Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP
Enzyme
PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate
H+ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP
Enzyme
PMID

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate
an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H+ + CMP
Enzyme
PMID
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:1574 alcohol use disorder
DOID:3070 high grade glioma
Ortholog
Displaying entries 51 - 60 of 214 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
102499508 246437_0:002ae2
102575767 8496_0:0043e1
102738156 9713_0:000938
102744344 9713_0:002f34
102753980 225400_0:0024a5
102838630 185453_0:0031df
102875488 28737_0:0010fd
102917784 230844_0:0037a7
102941507 8469_0:002a4e
102992136 9755_0:000126
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024