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MHC class I polypeptide-related sequence A

Summary

Gene Symbol

MICA

Aliases

PERB11.1

Organism

Homo sapiens (human)

External Links

NCBI Gene

100507436

HGNC

7090

KEGG Gene ID

hsa:100507436

PubChem

100507436

Alliance of Genome Resources

HGNC:7090

Annotation

Keyword

3D-structure
Adaptive immunity
Alternative splicing
Cell membrane
Cytolysis
Cytoplasm
Disulfide bond
Glycoprotein
Host-virus interaction
Immunoglobulin domain
Metal-binding
Palmitate
Proteomics identification
Reference proteome
Signal
Transmembrane helix
Ubl conjugation
Zinc

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q29983
Q96QC4
A0A0G2JJ55
A0A024RCL3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
antigen processing and presentation of endogenous peptide antigen via MHC class Ib	IBA
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	IBA
T cell mediated cytotoxicity	IDA	10426993
positive regulation of T cell mediated cytotoxicity	IBA
immune response to tumor cell	IDA	10359807

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

lymphocyte mediated immunity [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

T cell mediated immunity [inference]

T cell mediated cytotoxicity

immune response

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell mediated cytotoxicity

immune response to tumor cell

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

antigen processing and presentation [inference]

antigen processing and presentation via MHC class Ib [inference]

antigen processing and presentation of peptide antigen via MHC class Ib [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class Ib

antigen processing and presentation of endogenous antigen [inference]

antigen processing and presentation of endogenous peptide antigen [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class Ib

antigen processing and presentation of endogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

antigen processing and presentation of peptide antigen [inference]

antigen processing and presentation of peptide antigen via MHC class Ib [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class Ib

antigen processing and presentation of peptide antigen via MHC class I [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

antigen processing and presentation of endogenous peptide antigen [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class Ib

antigen processing and presentation of endogenous peptide antigen via MHC class I [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway [inference]

antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

killing of cells of another organism

signal transduction

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

T cell activation [inference]

gamma-delta T cell activation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

defense response to symbiont [inference]

defense response to virus

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

defense response to symbiont [inference]

defense response to virus

response to heat

cellular response to stress [inference]

cellular response to DNA damage stimulus

immune response

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell mediated cytotoxicity

immune response to tumor cell

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to tumor cell [inference]

immune response to tumor cell

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

defense response to symbiont [inference]

defense response to virus

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

negative regulation of natural killer cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of leukocyte mediated immunity [inference]

regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of T cell mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of lymphocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of T cell mediated immunity [inference]

regulation of T cell mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of cellular process [inference]

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of cellular process [inference]

negative regulation of cell killing [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

regulation of T cell mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of innate immune response [inference]

regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of innate immune response [inference]

negative regulation of natural killer cell mediated immunity [inference]

negative regulation of natural killer cell mediated cytotoxicity

regulation of cellular process [inference]

signal transduction

regulation of cell killing [inference]

regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of T cell mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

regulation of natural killer cell mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of cell killing [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

positive regulation of cellular process [inference]

positive regulation of cell killing [inference]

positive regulation of leukocyte mediated cytotoxicity [inference]

positive regulation of T cell mediated cytotoxicity

negative regulation of cellular process [inference]

negative regulation of cell killing [inference]

negative regulation of leukocyte mediated cytotoxicity [inference]

negative regulation of natural killer cell mediated cytotoxicity

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

negative regulation of natural killer cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

regulation of lymphocyte activation [inference]

regulation of natural killer cell activation [inference]

negative regulation of natural killer cell activation

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of natural killer cell activation

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
beta-2-microglobulin binding	IDA	8901601
protein binding	IPI	11323699 21712812
signaling receptor binding	IBA
metal ion binding
receptor ligand activity	IDA	11777960

GO Hierarchy

molecular function

binding [inference]

antigen binding [inference]

peptide antigen binding

protein binding

signaling receptor binding

beta-2-microglobulin binding

amide binding [inference]

peptide binding [inference]

peptide antigen binding

ion binding [inference]

cation binding [inference]

metal ion binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

MHC class I polypeptide-related sequence A

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
immune response
positive regulation of T cell mediated cytotoxicity
signaling receptor binding

Displaying **all 7** entries
InterPro
Immunoglobulin C1-set
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
MHC class I-like antigen recognition-like superfamily
MHC class I-like antigen recognition-like
MHC classes I/II-like antigen recognition protein

KEGG BRITE Database

Orthology

K07985

Name

MHC class I-related protein

References

8022771

Ortholog

Displaying entries **1 - 10** of 13 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	243864		MGI:2179989	MOUSE52922
Mus musculus	266815		MGI:2179988	MOUSE52826
Rattus norvegicus	292671		RGD:1311714	RATNO19320
Rattus norvegicus	365212		RGD:1564508
Pan troglodytes	450199			PANTR37676
Macaca mulatta	715141			MACMU33951
Macaca mulatta	100141395			MACMU33951
Danio rerio	100148359		ZFIN:ZDB-GENE-140820-7
Callithrix jacchus	100390841			CALJA31676
Pongo abelii	100438364	9601_0:001cfc		PONAB31024

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements