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N-acetylneuraminate pyruvate lyase

Summary

Gene Symbol

NPL

Organism

Meleagris gallopavo (turkey)

External Links

NCBI Gene: 100538535
KEGG Gene ID: mgp:100538535
PubChem: 100538535

Annotation

Keyword

Lyase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
G1MSX9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
N-acetylneuraminate catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
4-hydroxy-tetrahydrodipicolinate synthase activity	IEA	30032202
N-acetylneuraminate lyase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

oxo-acid-lyase activity [inference]

N-acetylneuraminate lyase activity

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

4-hydroxy-tetrahydrodipicolinate synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

4-hydroxy-2-oxoglutarate aldolase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
4-hydroxy-tetrahydrodipicolinate synthase activity
lyase activity

Displaying **all 2** entries
InterPro
Aldolase-type TIM barrel
DapA-like

KEGG BRITE Database

Orthology

K01639

Name

N-acetylneuraminate lyase [EC:4.1.3.3]

References

Rhea

aceneuramate

pyruvate + N-acetyl-D-mannosamine

Enzyme

4.1.3.3

PMID

Ortholog

Displaying entries **21 - 30** of 87 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Callithrix jacchus	100895053			CALJA15788
Otolemur garnettii	100954272			OTOGA15374
Pan paniscus	100978733			PANPA03289
Papio anubis	101011948			PAPAN19304
Saimiri boliviensis boliviensis	101037350			SAIBB09046
Takifugu rubripes	101066675			TAKRU27206
Felis catus	101091498			FELCA37559
Ovis aries	101104513			SHEEP03957
Octodon degus	101589758			OCTDE21868
Mustela putorius furo	101683028			MUSPF06764

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024