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adaptor related protein complex 1 subunit mu 2

Summary

Gene Symbol

AP1M2

Organism

Homo sapiens (human)

External Links

NCBI Gene

10053

PubChem

10053

Alliance of Genome Resources

HGNC:558

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
Golgi apparatus
Membrane
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9Y6Q5	AP-mu chain family member mu1B Adaptor protein complex AP-1 subunit mu-2 Adaptor-related protein complex 1 subunit mu-2 Clathrin assembly protein complex 1 mu-2 medium chain 2 Golgi adaptor HA1/AP1 adaptin mu-2 subunit Mu-adaptin 2 Mu1B-adaptin
Q53GI5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein targeting	TAS	10338135
intracellular protein transport	IEA
vesicle targeting	TAS	10338135
vesicle-mediated transport	NAS	27057418
vesicle-mediated transport	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport

protein secretion [inference]

basolateral protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

basolateral protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

basolateral protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

basolateral protein secretion

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport

protein secretion [inference]

basolateral protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

basolateral protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

basolateral protein secretion

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

secretion [inference]

secretion by cell [inference]

protein secretion [inference]

basolateral protein secretion

intracellular transport [inference]

intracellular protein transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

protein secretion [inference]

basolateral protein secretion

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

protein secretion [inference]

basolateral protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

basolateral protein secretion

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport

protein secretion [inference]

basolateral protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

basolateral protein secretion

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport

protein secretion [inference]

basolateral protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

basolateral protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

basolateral protein secretion

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
clathrin-coated vesicle	IBA
cytoplasmic vesicle membrane	TAS
trans-Golgi network membrane	NAS	27057418
trans-Golgi network membrane	TAS
intracellular membrane-bounded organelle	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

AP-type membrane coat adaptor complex [inference]

clathrin adaptor complex [inference]

AP-1 adaptor complex

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

trans-Golgi network membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16189514 25416956 33961781
clathrin adaptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

cargo adaptor activity [inference]

clathrin adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

complex, subunit

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
clathrin adaptor activity

Displaying **all 6** entries
InterPro
AP complex, mu/sigma subunit
AP-2 complex subunit mu, C-terminal superfamily
Clathrin adaptor, mu subunit, conserved site
Clathrin adaptor, mu subunit
Longin-like domain superfamily
Mu homology domain

Ortholog

Displaying entries **1 - 10** of 60 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	8907	SGD:S000006180
Xenopus tropicalis	10053	Xenbase:XB-GENE-946863
Mus musculus	11768		MOUSE62777
Rattus norvegicus	367038		RATNO39876
Danio rerio	403021		DANRE38346
Pan troglodytes	455710		PANTR17163
Bos taurus	515766		BOVIN32613
Canis lupus familiaris	611211		CANLF07854
Macaca mulatta	720531		MACMU20475
Monodelphis domestica	100012467		MONDO20392