GlyCosmos Portal

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GO Term	Evidence Code	PMID
zinc ion binding	IEA	30032202
cobalt ion binding	IEA	30032202
pyridoxal phosphate binding	IEA	22301074 30032202
mRNA 5'-UTR binding	IEA	30032202
glycine hydroxymethyltransferase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

hydroxymethyl-, formyl- and related transferase activity [inference]

glycine hydroxymethyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

serine binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

carboxylic acid binding [inference]

amino acid binding [inference]

serine binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

serine binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding [inference]

mRNA 5'-UTR binding

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

vitamin B6 binding [inference]

pyridoxal phosphate binding

translation regulator activity [inference]

translation repressor activity [inference]

mRNA regulatory element binding translation repressor activity

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Serine hydroxymethyltransferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 11 in total

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Gene Ontology
L-serine catabolic process
cobalt ion binding
folic acid metabolic process
glycine biosynthetic process from serine
glycine hydroxymethyltransferase activity
pyridoxal phosphate binding
serine binding
tetrahydrofolate interconversion
tetrahydrofolate metabolic process
transferase activity

Displaying **all 6** entries
InterPro
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase, small domain
Pyridoxal phosphate-dependent transferase
Serine hydroxymethyltransferase, pyridoxal phosphate binding site
Serine hydroxymethyltransferase-like domain
Serine hydroxymethyltransferase

Ortholog

Displaying entries **91 - 93** of 93 in total

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Species	Gene ID	OrthoDB
Moschus berezovskii	129553796	68408_0:002335
Bubalus kerabau	129650156	346063_0:000714
Hippopotamus amphibius kiboko	130833698	575201_0:003bca

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

OrthoDB (Group)

International Collaboration

Acknowledgements