GlyCosmos Portal

Submissions

inositol polyphosphate phosphatase like 1

Summary

Gene Symbol

INPPL1

Organism

Loxodonta africana (African savanna elephant)

External Links

NCBI Gene: 100673994
KEGG Gene ID: lav:100673994
PubChem: 100673994

Annotation

Keyword

Cell projection
Cytoskeleton
Immunity
Membrane
Reference proteome
SH2 domain

Proteins

Displaying 1 entry
UniProt	Protein Name
G3SMM4	Inositol polyphosphate phosphatase-like protein 1 Protein 51C SH2 domain-containing inositol 5'-phosphatase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
negative regulation of insulin-like growth factor receptor signaling pathway	IEA	30032202
phosphatidylinositol dephosphorylation	IEA	22301074
regulation of immune response	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

dephosphorylation [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

lipid modification [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

lipid modification [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

lipid modification [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

dephosphorylation [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

lipid modification [inference]

phospholipid dephosphorylation [inference]

phosphatidylinositol dephosphorylation

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

phosphatidylinositol dephosphorylation

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of insulin-like growth factor receptor signaling pathway [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of insulin-like growth factor receptor signaling pathway [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of immune response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

regulation of insulin-like growth factor receptor signaling pathway [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of insulin-like growth factor receptor signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
inositol-polyphosphate 5-phosphatase activity	IEA	30032202
protein binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

inositol phosphate phosphatase activity [inference]

inositol trisphosphate phosphatase activity [inference]

inositol-polyphosphate 5-phosphatase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
immune system process
inositol-polyphosphate 5-phosphatase activity
negative regulation of insulin-like growth factor receptor signaling pathway
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
regulation of immune response

Displaying **all 4** entries
InterPro
Endonuclease/exonuclease/phosphatase superfamily
Inositol polyphosphate-related phosphatase
SH2 domain superfamily
SH2 domain

KEGG BRITE Database

Orthology

K15909

Name

phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]

References

9660833

Rhea

RHEA:25528

H₂O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)

phosphate + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate)

Enzyme

3.1.3.86

PMID

Ortholog

Displaying entries **31 - 40** of 64 in total

« First

‹ Prev

1

2

3

4

5

6

7

Next ›

Last »
Species	Gene ID	Orthologous MAtrix
Capra hircus	102178924	CAPHI05630
Myotis lucifugus	102419220	MYOLU08605
Astyanax mexicanus	103027088	ASTMX04344
Chlorocebus sabaeus	103247996	CHLSB00778
Carlito syrichta	103249895	CARSF30126
Ursus maritimus	103678107	URSMA22169
Nannospalax galili	103750804	NANGA19203
Rhinopithecus roxellana	104665152	RHIRO02900
Pteropus vampyrus	105303690	PTEVA15025
Macaca nemestrina	105468700	MACNE12945