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alanine--glyoxylate and serine--pyruvate aminotransferase

Summary

Gene Symbol

AGXT

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 100855679
KEGG Gene ID: cfa:100855679
PubChem: 100855679

Annotation

Keyword

Pyridoxal phosphate

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A8C0PTY4	Serine--pyruvate aminotransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glycine biosynthetic process, by transamination of glyoxylate	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process, by transamination of glyoxylate

Displaying 1 entry
GO Term	Evidence Code	PMID
peroxisome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alanine-glyoxylate transaminase activity	IEA	30032202
serine-pyruvate transaminase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring nitrogenous groups [inference]

transaminase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Aminotransferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
alanine-glyoxylate transaminase activity
glycine biosynthetic process, by transamination of glyoxylate

Displaying **all 6** entries
InterPro
Aminotransferase class V domain
Aminotransferase class-V, pyridoxal-phosphate binding site
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase, small domain
Pyridoxal phosphate-dependent transferase
Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase

KEGG BRITE Database

Orthology

K00830

Name

alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]

References

Rhea

glyoxylate + L-alanine

pyruvate + glycine

Enzyme

2.6.1.44

PMID

pyruvate + L-serine

3-hydroxypyruvate + L-alanine

Enzyme

2.6.1.51

PMID

2-oxobutanoate + L-alanine

pyruvate + (2S)-2-aminobutanoate

Enzyme

2.6.1.44

PMID

2123486

Ortholog

Displaying entries **1 - 10** of **102** in total

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Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	189			HUMAN67945
Mus musculus	11611			MOUSE29711
Rattus norvegicus	24792			RATNO42827
Danio rerio	436603			DANRE38168
Macaca mulatta	699941			MACMU06887
Felis catus	727692	9685_0:002432		FELCA21109
Bos taurus	789572			BOVIN27501
Equus caballus	100067459			HORSE36897
Ornithorhynchus anatinus	100080454			ORNAN24310
Pongo abelii	100171897			PONAB24756

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Last updated: December 9, 2024