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ORMDL sphingolipid biosynthesis regulator 1

Summary

Gene Symbol

ORMDL1

Organism

Capra hircus (goat)

External Links

NCBI Gene: 100861146
KEGG Gene ID: chx:100861146
PubChem: 100861146

Annotation

Keyword

Endoplasmic reticulum
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A452EH98

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular sphingolipid homeostasis	IEA	30032202
negative regulation of ceramide biosynthetic process	IEA	30032202
ceramide metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

lipid homeostasis [inference]

intracellular sphingolipid homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of lipid biosynthetic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of lipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of amide metabolic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of membrane lipid metabolic process [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of cellular component biogenesis [inference]

regulation of sphingolipid biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

regulation of ceramide biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of sphingolipid biosynthetic process [inference]

negative regulation of ceramide biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
SPOTS complex	IEA	30032202
endoplasmic reticulum membrane	IEA	22301074 30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

endoplasmic reticulum protein-containing complex [inference]

endoplasmic reticulum palmitoyltransferase complex [inference]

serine C-palmitoyltransferase complex [inference]

SPOTS complex

catalytic complex [inference]

transferase complex [inference]

palmitoyltransferase complex [inference]

endoplasmic reticulum palmitoyltransferase complex [inference]

serine C-palmitoyltransferase complex [inference]

SPOTS complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **41 - 50** of 93 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Tursiops truncatus	101332629		TURTR11036
Balaenoptera musculus	118898420		BALMU00509
Loxodonta africana	100669827		LOXAF18860
Equus caballus	100069307		HORSE13471
Sus scrofa	100155491		PIGXX09659
Bos taurus	768077		BOVIN23898
Ovis aries	101112289		SHEEP09329
Dipodomys ordii	105996321		DIPOR00571
Cricetulus griseus	100767133		CRIGR24415
Mus musculus	227102		MOUSE27997

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Last updated: August 19, 2024