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N-acetylneuraminate pyruvate lyase

Summary

Gene Symbol

Organism

Otolemur garnettii (small-eared galago)

External Links

NCBI Gene: 100954272
KEGG Gene ID: oga:100954272
PubChem: 100954272

Annotation

Keyword

Lyase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
H0WL45	N-acetylneuraminate pyruvate-lyase N-acetylneuraminic acid aldolase Sialate lyase Sialate-pyruvate lyase Sialic acid aldolase Sialic acid lyase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
N-acetylneuraminate catabolic process	IEA	30032202
carbohydrate metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

carbohydrate derivative catabolic process [inference]

amino sugar catabolic process [inference]

N-acetylneuraminate catabolic process

organonitrogen compound catabolic process [inference]

N-acetylneuraminate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

N-acetylneuraminate metabolic process [inference]

N-acetylneuraminate catabolic process

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

N-acetylneuraminate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
4-hydroxy-tetrahydrodipicolinate synthase activity	IEA	30032202
N-acetylneuraminate lyase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

oxo-acid-lyase activity [inference]

N-acetylneuraminate lyase activity

carbon-oxygen lyase activity [inference]

hydro-lyase activity [inference]

4-hydroxy-tetrahydrodipicolinate synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

4-hydroxy-2-oxoglutarate aldolase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
4-hydroxy-tetrahydrodipicolinate synthase activity
lyase activity

Displaying **all 2** entries
InterPro
Aldolase-type TIM barrel
DapA-like

KEGG BRITE Database

Orthology

K01639

Name

N-acetylneuraminate lyase [EC:4.1.3.3]

References

Rhea

RHEA:23296

aceneuramate

pyruvate + N-acetyl-D-mannosamine

Enzyme

4.1.3.3

PMID

Ortholog

Displaying entries **11 - 20** of 79 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Danio rerio	100148292		DANRE43710
Pongo abelii	100171523	9601_0:0002c3	PONAB16955
Salmo salar	100194810		SALSA10498
Taeniopygia guttata	100224822		TAEGU29158
Ailuropoda melanoleuca	100469753		AILME12628
Meleagris gallopavo	100538535		MELGA02072
Anolis carolinensis	100559732		ANOCA17746
Nomascus leucogenys	100605321	61853_0:001bd4	NOMLE37737
Loxodonta africana	100672144		LOXAF13683
Cavia porcellus	100734839		CAVPO07026

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Acknowledgements