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phospholipase C beta 1

Summary

Gene Symbol

PLCB1

Organism

Pan paniscus (pygmy chimpanzee)

External Links

NCBI Gene: 100969660
KEGG Gene ID: pps:100969660
PubChem: 100969660

Annotation

Keyword

Calcium
Hydrolase
Lipid degradation
Metal-binding
Phosphoprotein
Reference proteome
Transducer

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2R8ZNS9
A0A2R8ZKZ8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
release of sequestered calcium ion into cytosol	IEA	30032202
memory	IEA	30032202
phosphatidylinositol-mediated signaling	IEA	30032202
lipid catabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol-mediated signaling

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory

behavior [inference]

learning or memory [inference]

memory

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol-mediated signaling

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202
nuclear speck	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

nuclear body [inference]

nuclear speck

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA	22301074
phosphatidylinositol phospholipase C activity	IEA	22301074 30032202
calmodulin binding	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

binding [inference]

protein binding [inference]

calmodulin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K05858

Name

phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]

References

Rhea

RHEA:33179

H₂O + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate)

H⁺ + a 1,2-diacyl-sn-glycerol + 1D-myo-inositol 1,4,5-trisphosphate

Enzyme

3.1.4.11

PMID

Ortholog

Displaying entries **31 - 40** of 71 in total

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Species	Gene ID	Orthologous MAtrix
Balaenoptera musculus	118881571	BALMU20704
Equus caballus	100051558	HORSE21214
Sus scrofa	100152679	PIGXX11241
Bos taurus	287026	BOVIN04202
Capra hircus	102188148	CAPHI03220
Ovis aries	101103585	SHEEP04084
Dipodomys ordii	105981715	DIPOR03468
Cricetulus griseus	100751979	CRIGR00465
Mus musculus	18795	MOUSE35321
Rattus norvegicus	24654	RATNO26941