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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
purinergic receptor P2X 4
Summary
- Gene Symbol
-
- P2RX4
- Organism
- Pan paniscus (pygmy chimpanzee)
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Lysosome
- Receptor
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A2R9CK77 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to fluid shear stress |
|
|
| cellular response to ATP |
|
|
| negative regulation of cardiac muscle hypertrophy |
|
|
| positive regulation of calcium-mediated signaling |
|
|
| regulation of blood pressure |
|
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear inner membrane | ||
| postsynapse |
|
|
| plasma membrane | ||
| perinuclear region of cytoplasm |
|
|
| lysosomal membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| ligand-gated calcium channel activity |
|
|
| purinergic nucleotide receptor activity | ||
| identical protein binding |
|
|
| extracellularly ATP-gated monoatomic cation channel activity | ||
| ATP binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Hominidae
- Group Name
- P2X purinoceptor 4
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| response to ATP |
| response to fluid shear stress |
| InterPro |
|---|
| P2X purinoreceptor extracellular domain superfamily |
| P2X purinoreceptor |
| P2X4 purinoceptor |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5025 | 9606_0:004c83 | HUMAN15907 | ||
| 18438 | MOUSE43460 | |||
| 29659 | RATNO05042 | |||
| 338036 | BOVIN09473 | |||
| 448783 | CANLF10290 | |||
| 452319 | 9598_0:0037b9 | |||
| 497623 | PIGXX06798 | |||
| 702536 | MACMU03941 | |||
| 100008720 | RABIT09132 | |||
| 100059626 | HORSE40814 |
