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phospholipase C epsilon 1

Summary

Gene Symbol

PLCE1

Organism

Pan paniscus (pygmy chimpanzee)

External Links

NCBI Gene: 100992707
KEGG Gene ID: pps:100992707
PubChem: 100992707

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
phosphatidylinositol-mediated signaling	IEA	30032202
release of sequestered calcium ion into cytosol	IEA	30032202
small GTPase mediated signal transduction	IEA	22301074
lipid metabolic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process

organic substance metabolic process [inference]

lipid metabolic process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
guanyl-nucleotide exchange factor activity	IEA	22301074
phosphatidylinositol phospholipase C activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

phospholipase C activity [inference]

phosphatidylinositol phospholipase C activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

guanyl-nucleotide exchange factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1, EF-hand domain

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 15 in total

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Gene Ontology
Ras protein signal transduction
calcium-mediated signaling
diacylglycerol biosynthetic process
enzyme binding
epidermal growth factor receptor signaling pathway
glomerulus development
hydrolase activity
lipid metabolic process
metal ion binding
phosphatidylinositol phospholipase C activity

KEGG BRITE Database

Orthology

K05860

Name

phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]

References

Ortholog

Displaying entries **21 - 30** of 65 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Otolemur garnettii	100947727		OTOGA17252
Papio anubis	101018828		PAPAN04740
Saimiri boliviensis boliviensis	101043700		SAIBB04520
Takifugu rubripes	101065955		TAKRU24939
Felis catus	101088695		FELCA27297
Ovis aries	101105703		SHEEP11458
Gorilla gorilla gorilla	101125007	9595_0:0030d7	GORGO01278
Tursiops truncatus	101338810		TURTR12620
Octodon degus	101588282		OCTDE02808
Mustela putorius furo	101689486		MUSPF14792