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proprotein convertase subtilisin/kexin type 9

Summary

Gene Symbol

PCSK9

Organism

Saimiri boliviensis (Bolivian squirrel monkey)

External Links

NCBI Gene: 101049523
PubChem: 101049523

Annotation

Keyword

Apoptosis
Autocatalytic cleavage
Calcium
Cholesterol metabolism
Cytoplasm
Disulfide bond
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Lysosome
Phosphoprotein
Reference proteome
Secreted
Serine protease
Signal
Sulfation
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
A8T695	Proprotein convertase 9 Subtilisin/kexin-like protease PC9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
kidney development
liver development
negative regulation of receptor recycling
negative regulation of receptor internalization
positive regulation of receptor internalization

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

lipoprotein metabolic process

protein maturation [inference]

protein processing [inference]

protein autoprocessing

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

catabolic process [inference]

cellular catabolic process [inference]

receptor catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

receptor catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular catabolic process [inference]

receptor catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

phospholipid metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

phospholipid metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

lipoprotein metabolic process

protein maturation [inference]

protein processing [inference]

protein autoprocessing

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

phospholipid metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

receptor catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

lipoprotein metabolic process

protein maturation [inference]

protein processing [inference]

protein autoprocessing

receptor metabolic process [inference]

low-density lipoprotein receptor particle metabolic process [inference]

low-density lipoprotein particle receptor catabolic process

receptor catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing [inference]

protein autoprocessing

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

lipoprotein metabolic process

protein maturation [inference]

protein processing [inference]

protein autoprocessing

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

receptor catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular catabolic process [inference]

receptor catabolic process [inference]

low-density lipoprotein particle receptor catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

phospholipid metabolic process

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

kidney development

gland development [inference]

liver development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of receptor recycling

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of receptor catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of protein catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of receptor catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of macromolecule metabolic process [inference]

regulation of receptor recycling [inference]

negative regulation of receptor recycling

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of receptor recycling

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of receptor catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of signaling [inference]

regulation of receptor recycling [inference]

negative regulation of receptor recycling

regulation of signal transduction [inference]

regulation of signaling receptor activity

negative regulation of signaling [inference]

negative regulation of receptor recycling

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of sterol transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of cholesterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular sterol transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular lipid transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular sterol transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular transport [inference]

regulation of intracellular lipid transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular sterol transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of receptor-mediated endocytosis involved in cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

negative regulation of sodium ion transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of receptor-mediated endocytosis [inference]

regulation of receptor-mediated endocytosis involved in cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular lipid transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular sterol transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of receptor-mediated endocytosis involved in cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of lipid localization [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of sterol transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of cholesterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular sterol transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular lipid transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular sterol transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of receptor recycling

negative regulation of signaling [inference]

negative regulation of receptor recycling

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of monoatomic ion transport [inference]

negative regulation of sodium ion transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of lipoprotein particle clearance [inference]

negative regulation of low-density lipoprotein particle clearance

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of sterol transport [inference]

negative regulation of cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of signaling receptor activity

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of cellular catabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of receptor catabolic process [inference]

regulation of low-density lipoprotein particle receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

regulation of neuron apoptotic process

positive regulation of neuron apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular catabolic process [inference]

positive regulation of receptor catabolic process [inference]

positive regulation of low-density lipoprotein particle receptor catabolic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of neuron apoptotic process

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of transmembrane transport [inference]

negative regulation of monoatomic ion transmembrane transport [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cation transmembrane transport [inference]

negative regulation of sodium ion transmembrane transport [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of receptor-mediated endocytosis [inference]

regulation of receptor-mediated endocytosis involved in cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular lipid transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular sterol transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of intracellular cholesterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

negative regulation of intracellular transport [inference]

negative regulation of intracellular lipid transport [inference]

negative regulation of intracellular sterol transport [inference]

negative regulation of intracellular cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of receptor-mediated endocytosis involved in cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

negative regulation of receptor-mediated endocytosis [inference]

regulation of receptor-mediated endocytosis involved in cholesterol transport [inference]

negative regulation of receptor-mediated endocytosis involved in cholesterol transport

regulation of multicellular organismal process [inference]

regulation of lipoprotein particle clearance [inference]

negative regulation of lipoprotein particle clearance [inference]

negative regulation of low-density lipoprotein particle clearance

regulation of low-density lipoprotein particle clearance [inference]

negative regulation of low-density lipoprotein particle clearance

negative regulation of multicellular organismal process [inference]

negative regulation of lipoprotein particle clearance [inference]

negative regulation of low-density lipoprotein particle clearance

regulation of molecular function [inference]

regulation of signaling receptor activity

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

regulation of sodium ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of molecular function [inference]

negative regulation of transporter activity [inference]

negative regulation of ion transmembrane transporter activity [inference]

negative regulation of sodium ion transmembrane transporter activity

negative regulation of low-density lipoprotein receptor activity

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
extracellular space	IEA	30032202
cytoplasm
lysosome
early endosome
late endosome

GO Hierarchy

cellular component

protein-containing complex [inference]

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
serine-type endopeptidase activity	IEA	22301074 30032202
sodium channel inhibitor activity
low-density lipoprotein particle binding
signaling receptor inhibitor activity
apolipoprotein binding