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N-glycanase 1

Summary

Gene Symbol

NGLY1

Organism

Felis catus (domestic cat)

External Links

NCBI Gene: 101086171
KEGG Gene ID: fca:101086171
PubChem: 101086171

Annotation

Keyword

Cytoplasm
Hydrolase
Metal-binding
Reference proteome
Zinc

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A337S594	N-glycanase 1 Peptide:N-glycanase
M3WX23	N-glycanase 1 Peptide:N-glycanase
A0A337S5I9	N-glycanase 1 Peptide:N-glycanase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein quality control for misfolded or incompletely synthesized proteins	IEA	30032202
protein deglycosylation	IEA	30032202
glycoprotein catabolic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

macromolecule modification [inference]

protein modification process [inference]

protein deglycosylation

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

glycoprotein metabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein modification process [inference]

protein deglycosylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	IEA	30032202
cytoplasm	IEA	22301074
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying 1 entry
GO Term	Evidence Code	PMID
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [inference]

peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01456

Name

peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52]

References

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GlyCosmos Portal v4.1.1

Last updated: February 17, 2025

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Acknowledgements