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propionyl-CoA carboxylase subunit alpha

Summary

Gene Symbol

PCCA

Organism

Gorilla gorilla gorilla (western lowland gorilla)

External Links

NCBI Gene: 101127469
KEGG Gene ID: ggo:101127469
PubChem: 101127469

Annotation

Keyword

ATP-binding
Acetylation
Biotin
Ligase
Lipid degradation
Magnesium
Manganese
Metal-binding
Mitochondrion
Phosphoprotein
Reference proteome
Transit peptide

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2I2YJZ1	Propanoyl-CoA:carbon dioxide ligase subunit alpha
G3R9X1	Propanoyl-CoA:carbon dioxide ligase subunit alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
propionyl-CoA carboxylase activity	IEA	30032202
ATP binding	IEA	22301074
metal ion binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-carbon bonds [inference]

CoA carboxylase activity [inference]

propionyl-CoA carboxylase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:23720

hydrogencarbonate + ATP + propanoyl-CoA

H⁺ + phosphate + ADP + (S)-methylmalonyl-CoA

Enzyme

6.4.1.3

PMID

16492739

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Last updated: April 6, 2026

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