GlyCosmos Portal

Submissions

serine hydroxymethyltransferase 2

Summary

Gene Symbol

SHMT2

Organism

Gorilla gorilla gorilla (western lowland gorilla)

External Links

NCBI Gene: 101134424
KEGG Gene ID: ggo:101134424
PubChem: 101134424

Annotation

Keyword

Acetylation
Cytoplasm
One-carbon metabolism
Pyridoxal phosphate
Reference proteome
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
G3R410

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
regulation of oxidative phosphorylation	IEA	30032202
L-serine catabolic process	IEA	30032202
glycine biosynthetic process from serine	IEA	22301074 30032202
response to type I interferon	IEA	30032202
tetrahydrofolate interconversion	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

folic acid metabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle metabolic process [inference]

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

folic acid metabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic cyclic compound metabolic process [inference]

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle metabolic process [inference]

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to type I interferon

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of generation of precursor metabolites and energy [inference]

regulation of cellular respiration [inference]

regulation of aerobic respiration [inference]

regulation of oxidative phosphorylation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of generation of precursor metabolites and energy [inference]

regulation of cellular respiration [inference]

regulation of aerobic respiration [inference]

regulation of oxidative phosphorylation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202
mitochondrial inner membrane	IEA	30032202
mitochondrial matrix	IEA	30032202
BRISC complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

BRISC complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glycine hydroxymethyltransferase activity	IEA	22301074 30032202
zinc ion binding	IEA	30032202
pyridoxal phosphate binding	IEA	22301074 30032202
cobalt ion binding	IEA	30032202
serine binding	IEA	30032202