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stearoyl-CoA desaturase

Summary

Gene Symbol

SCD

Organism

Gorilla gorilla gorilla (western lowland gorilla)

External Links

NCBI Gene: 101138141
KEGG Gene ID: ggo:101138141
PubChem: 101138141

Annotation

Keyword

Fatty acid biosynthesis
Iron
Metal-binding
Oxidoreductase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
G3QFK6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
monounsaturated fatty acid biosynthetic process	IEA	30032202
unsaturated fatty acid biosynthetic process	IEA	30032202
response to fatty acid	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid biosynthetic process [inference]

unsaturated fatty acid metabolic process [inference]

unsaturated fatty acid biosynthetic process

monounsaturated fatty acid metabolic process [inference]

monounsaturated fatty acid biosynthetic process

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to lipid [inference]

response to fatty acid

response to oxygen-containing compound [inference]

response to fatty acid

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
palmitoyl-CoA 9-desaturase activity	IEA	30032202
iron ion binding	IEA	30032202
stearoyl-CoA 9-desaturase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [inference]

acyl-CoA desaturase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Hominidae
Group Name: Fatty acid desaturase type 1, conserved site

Displaying **all 8** entries
Gene Ontology
iron ion binding
metal ion binding
monounsaturated fatty acid biosynthetic process
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
oxidoreductase activity
palmitoyl-CoA 9-desaturase activity
response to fatty acid
unsaturated fatty acid biosynthetic process

Displaying **all 2** entries
InterPro
Acyl-CoA desaturase
Fatty acid desaturase type 1, conserved site

KEGG BRITE Database

Orthology

K00507

Name

stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]

References

Rhea

H⁺ + O₂ + octadecanoyl-CoA

H₂O + (9Z)-octadecenoyl-CoA

Enzyme

1.14.19.1

PMID

Ortholog

Displaying entries **1 - 10** of 39 in total

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Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6319	9606_0:00424e		HUMAN02504
Bos taurus	280924			BOVIN21358
Sus scrofa	396670			PIGXX08335
Ovis aries	443185			SHEEP11528
Pan troglodytes	450676	9598_0:002ccf		PANTR01360
Macaca mulatta	710155			MACMU45502
Monodelphis domestica	100014196			MONDO05450
Ornithorhynchus anatinus	100082486			ORNAN07846
Papio anubis	100126751			PAPAN03952
Pongo abelii	100172656	9601_0:0029ef		PONAB01407

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024